Guterres made the comments at the start of a virtual meeting of the 73rd World Health Assembly on Monday.
"Different countries have followed different, sometimes contradictory strategies and we are all paying a heavy price," the UN chief said, adding, "Many countries have ignored the recommendations of the World Health Organization. As a result, the virus has spread across the world."
Guterres further described the coronavirus crisis as the “greatest challenge of our age," noting that the pandemic has demonstrated the fragility of the world.
Despite great scientific and technological advances in recent decades, a virus has "brought us to our knees," the UN chief said, urging countries to be more united in responding to the pandemic.
The new coronavirus, which causes a respiratory disease known as COVID-19, emerged in the city of Wuhan in December last year, incrementally affecting the rest of the world.
The virus has so far infected 4,847,000 people worldwide, and over 317,700 have died, according to a running count by worldometers.info.
Guterres further said the coronavirus pandemic should serve as a "wake-up call" to the world, urging countries to be more united in responding to the crisis.
"COVID-19 must be a wake-up call. It is time for an end to the hubris," he said, adding, "We have seen some solidarity, but very little unity in our response to COVID-19."
Russian army sets up mobile hospital to fight coronavirus at Siberian gold mine
Russia's defense ministry is setting up a mobile field hospital at the largest Siberian mine of the country's top gold producer, Polyus, to treat miners who contract the new coronavirus, the company said on Monday.
Russia produces dozens of metals for global markets and the decision to open the field hospital at the mine underlines its concern to maintain smooth production amid the pandemic.
The mobile field hospital will have the capacity to treat up to 1,100 people at the Olimpiada mine, which is located 550 km (342 miles) north of the city of Krasnoyarsk, Polyus said.
"The unit continues working, production processes are being carried out in a continuous mode," Polyus told Reuters.
Separately, Russia's defense ministry said it would send around 400 servicemen to set up and operate the field hospital, including 77 medical personnel.
Growth of new coronavirus cases stopped: Russian PM
Prime Minister Mikhail Mishustin says the growth in new coronavirus cases has been stopped in Russia, which has recorded the world's largest number of infections after the United States.
"The situation with the spread of the coronavirus infection remains difficult, but we can still acknowledge that we managed to put a stop to the growth of infections," Mishustin told a government meeting on Monday.
Russia on Monday reported under 9,000 virus infections for the first time since the beginning of May, after seeing a steady daily rise of around 10,000 cases for more than two weeks.